Kimberly Ashayeri, J. Alex Thomas, Brett Braly, Nicholas O’Malley, Carlos Leon, Ivan Cheng, Brian Kwon, Mark Medley, Leon Eisen, Themistocles S. Protopsaltis, Aaron J. Buckland

May 2022, pp 1 - 12 Supplement Article Read Full Article 10.1007/s00586-022-07226-7

First Online: 13 May 2022


This study compares perioperative and 1-year outcomes of lateral decubitus single position circumferential fusion (L-SPS) versus minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) for degenerative pathologies.


Multicenter retrospective chart review of patients undergoing AP fusion with L-SPS or MIS TLIF. Demographics and clinical and radiographic outcomes were compared using independent samples t tests and chi-squared analyses with significance set at p 


A total of 445 patients were included: 353 L-SPS, 92 MIS TLIF. The L-SPS cohort was significantly older with fewer diabetics and more levels fused. The L-SPS cohort had significantly shorter operative time, blood loss, radiation dosage, and length of stay compared to MIS TLIF. 1-year follow-up showed that the L-SPS cohort had higher rates of fusion (97.87% vs. 81.11%; p = 0.006) and lower rates of subsidence (6.38% vs. 38.46%; p 

Similar results were seen after propensity-matched analysis and sub-analysis of cases including L5-S1.


L-SPS improves perioperative outcomes and does not compromise clinical or radiographic results at 1-year follow-up compared with MIS TLIF. There may be decreased rates of early mechanical failure with L-SPS.

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